| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | RESPIRATORY CHAIN COMPLEXES: STRUCTURE, FUNCTION, AND MECHANISMS |
| 7:30 pm - 7:50 pm | Discussion Leader: Tomoko Ohnishi (U. of Pennsylvania School of Medicine, PA, US) |
| 7:50 pm - 8:20 pm | Leonid Sazanov (Dunn Human Nutrition Unit, Cambridge, UK)
"Architecture of iron-sulfur clusters in complex I (as revealed by X-ray crystallography)" |
| 8:20 pm - 8:50 pm | Ulrich Brandt (University of Frankfurt, Germany)
"Bioenergetic and cellular aspects of mitochondrial complex I" |
| 8:50 pm - 9:20 pm | Edward Berry (Lawrence Berkeley National Lab, US)
"Crystallographic studies of active sites of mitochondrial complexes II and III" |
| 9:20 pm - 9:30 pm | General discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | BIOENERGETICS, METABOLISM, AND DISEASE |
| 9:00 am - 9:30 am | Discussion Leader: David Nicholls (Buck Institute for Age Research, CA, US) |
| 9:30 am - 10:00 am | Eric Schon (Columbia University, NY, US)
"Copper, redox sensing, and mitochondrial disease" |
| 10:00 am - 10:30 am | Martin Brand (MRC Cambridge, UK)
"Regulation of mitochondrial uncoupling proteins" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Daniel Ricquier (CNRS, Paris, France)
"Biology of mitochondrial uncoupling proteins" |
| 11:30 am - 12:00 pm | Valina Dawson (Johns Hopkins School of Medicine, MD, US)
"Poly (ADP-ribosyl)ation in the survival and death of neurons" |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | METAL ION HOMEOSTASIS AND MITOCHONDRIAL FUNCTION |
| 7:30 pm - 8:00 pm | Discussion Leader: Edith Gralla (UCLA, CA, US) |
| 8:00 pm - 8:30 pm | Sabeeha Merchant (UCLA, CA, US)
"Prioritized allocation of copper to respiration vs. photosynthesis" |
| 8:30 pm - 9:00 pm | Jerry Kaplan (Univ. of Utah, UT, US)
"Cellular mechanisms of iron sensing and homeostasis" |
| 9:00 pm - 9:30 pm | General Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | V-ATPases AND F1Fo-ATP SYNTHASES: STRUCTURE, FUNCTION, AND MECHANISM |
| 9:00 am - 9:30 am | Discussion Leader: Brian Cain (University of Florida, US) |
| 9:30 am - 10:00 am | Stephan Wilkens (UC Riverside, CA, US)
"Electron microscopy and NMR studies of F- and V-type ATPases" |
| 10:00 am - 10:30 am | Bettina Bottcher (EMBL, Heidelberg, Germany)
"Stator structure in F- and V-type ATPases" |
| 10:30 am | Coffee Break |
| 10:50 am - 11:20 am | Nathan Nelson (Tel Aviv University, Israel)
"Structure and mechanism of action of V-ATPases" |
| 11:20 am - 11:50 am | Masasuki Yoshida (Yokoyama, Japan)
"Structural requirements for rotational catalysis in ATPases" |
| 11:50 am - 12:05 pm | Richard Cross (SUNY Upstate Medical Univ., NY, USA)
"Multi-site Catalysis by MF1-ATPase" |
| 12:05 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | BIOENERGETICS OF CELLULAR pH CONTROL |
| 7:30 pm - 7:50 pm | Discussion Leader: Michael Forgac (Tufts University, MA, US) |
| 7:50 pm - 8:20 pm | Rajini Rao (Johns Hopkins Univ. School of Medicine, MD, US)
"pHome, Na+/H+ exchange and vesicle trafficking" |
| 8:20 pm - 8:50 pm | Fiona Karet (Univ. of Cambridge, UK)
"Energy-dependent renal acid-base handling: Lessons from inherited diseases" |
| 8:50 pm - 9:20 pm | Raul Martinez-Zaguilan (Texas Tech Univ. Health Science Center, TX, US)
"Plasmalemmal vacuolar H+-ATPase in angiogenesis and cancer" |
| 9:20 pm - 9:30 pm | General Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | POSTER DISCUSSIONS |
| 9:00 am - 10:40 am | A. ATPases (structure and function) |
| Discussion leaders: L. Shannon Holliday (U. of Florida, FL, US) & Terry Krulwich (Mt. Sinai School of Med., NY, US) |
| B. Respiratory chain (structure and function) |
| Discussion leaders: Bob Gennis (U. of Illinois, IL, US) & Diego Gonzalez-Halphen (Universidad Nacional Autonoma de Mexico, MX) |
| 10:40 am | Coffee Break |
| 11:00 am - 12:30 pm | C. Cellular Bioenergetics (combined session) |
| Discussion leaders: L. Shannon Holliday, Terry Krulwich, Bob Gennis, Diego Gonzalez-Halphen |
| Selected poster presenters will have an opportunity to present their work in short talks followed by discussion. |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ASSEMBLY OF RESPIRATORY CHAIN COMPLEXES |
| 7:30 pm - 7:50 pm | Discussion Leader: Rosemary Stuart (Marquette Univ, WI, US) |
| 7:50 pm - 8:20 pm | Antoni Barrientos (Univ. of Miami, Miami, FL, US)
"New insights into the COX assembly process in S. cerevisiae" |
| 8:20 pm - 8:50 pm | Carlos Moraes (Univ. of Miami, Miami, FL, US)
"OXPHOS complex homeostasis" |
| 8:50 pm - 9:20 pm | Thomas Langer (University of Koeln, Germany)
"Proteolytic control of mitochondrial biogenesis" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GENOMIC AND PROTEOMIC APPROACHES TO BIOENERGETICS |
| 9:00 am - 9:30 am | Discussion Leader: Andre Goffeau (Universite Catholique de Louvain, Belgium) |
| 9:30 am - 10:00 am | Brad Gibson (Buck Institute for Aging Research, CA, US)
"Mitochondrial proteomics, aging, and neurodegenerative disease" |
| 10:00 am - 10:30 am | Brigitte Meunier (Wolfson Institute for Biomedical Research, UK)
"Probing effects of disease mutations in bc1 complex using S. cerevisiae as a model system" |
| 10:30 am | Coffee Break |
| 11:00 am - 11:30 am | Volker Mueller (University of Frankfurt, Germany)
"Life in boiling water in the early history of life: How archaea synthesize ATP" |
| 11:30 am - 11:45 am | Beth Lee (Ohio State University, US)
"Selective stabilization of mammalian mRNAs during cellular energy depletion" |
| 11:45 am - 12:00 pm | Ozlem Onder (Univ. of Pennsylvania, PA)
"Proteome analysis of a Rhodobacter capsulatus DsbA-mutant reveals a deleterious overproduction of DegP" |
| 12:00 pm - 12:30 pm | General Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | NEW FRONTIERS IN MITOCHONDRIAL BIOLOGY |
| 7:30 pm - 7:50 pm | Discussion Leader: Andrei Vinogradov (Moscow State Univ., Russia) |
| 7:50 pm - 8:20 pm | Ronald Butow (U. of Texas, Southwestern Medical Center, TX, US)
"Mitochondrial signaling: Cellular adaptations to changes in the functional state of mitochondria" |
| 8:20 pm - 8:50 pm | Vamsi Mootha (Harvard Medical School, Boston, MA, US)
"Genomic approaches to mitochondrial biogenesis" |
| 8:50 pm - 9:20 pm | David Chan (California Institute of Technology, Pasadena, CA, US)
"Mitochondria fission and fusion" |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
