Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Cytoskeletal Ensembles Across Scales and Dimensions
7:40 pm - 8:25 pm
"Mechanisms of Mitosis and Size Control in Xenopus "
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Actin-Driven Endocytosis: Below 10 Seconds and Under the Diffraction Limit"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Architecture Dependence of Actin Assembly and Disassembly"
9:25 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emergent Properties in Two Dimensions: Complex Behaviors in the Cell Cortex and Cortex Models
9:00 am - 9:20 am
"Cellular Form: The Basis of Healthy Function"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Cleavage Furrow Organization in Xenopus Eggs and Extract"
9:45 am - 9:50 am
Discussion
9:50 am - 10:00 am
"The Structure of Melanoregulin Reveals a Role for Cholesterol Recognition in the Protein's Ability to Promote Dynein Function"
10:00 am - 10:05 am
Discussion
10:05 am - 10:25 am
"An Excitable Cortex Is an Adaptive Trait to Optimize Egg Size and Developmental Time to Larval Body Plan"
10:25 am - 10:30 am
Discussion
10:30 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Active Matters: Probing Forces, Fluctuations and Self-Organization in Actin Cortices"
11:05 am - 11:10 am
Discussion
11:10 am - 11:20 am
"Drosophila Syncytial Cleavage Furrows Require an Actomyosin Scaffold Patterned by Circumferential Displacement and Myosin Phospho-Regulation"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Positive Feedback Between the Contractile Ring and the Cell Cortex Drives Cytokinesis"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Phase Separation Enhances Arp2/3 Complex-Dependent Actin Polymerization by Increasing the Membrane Dwell Time of N-WASP"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Active Stress Coordinates Steady States and Contractile Flows in Actomyosin Networks"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Corralling Forces, Signals and Targets During Cell Division
7:30 pm - 7:50 pm
"Cell Division: Mechanical Integrity with Dynamic Parts"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Septin Ring in Budding Yeast: How and Why"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Chromosome Bridge Resolution Requires Mechanical Forces from Actin-Based Contractility"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Making and Breaking Kinetochore-Microtubule Attachments in Mitosis"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Actin and Microtubules Cooperate to Capture Chromosomes in the Large Oocyte Nucleus"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emergent Properties in One Dimension: Mechanisms that Bestow Sophistication upon Motors and Polymers
9:00 am - 9:20 am
"Molecular-Scale Microtubule Interactions with the α-Tubulin Acetyltransferase Enzyme αTAT1 Alter Cellular-Scale Acetylation Selectivity"
9:20 am - 9:25 am
Discussion
9:25 am - 9:45 am
"Effects of Nucleotide, Polymerization and Mutation on Actin Structure"
9:45 am - 9:50 am
Discussion
9:50 am - 10:10 am
"Structural Mechanism of a Force-Sensitive Myosin"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"She1 Affects Dynein Motility Through Simultaneous Interactions with the Microtubule and the Dynein Microtubule-Binding Domain"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Group Photo / Coffee Break
11:00 am - 11:20 am
"Nanometer-Scale Mechanisms for Controlling Micron-Scale Coordination and Changes in Actin and Microtubule Networks"
11:20 am - 11:25 am
Discussion
11:25 am - 11:35 am
"Biochemical Characterization of Actin Assembly by the Drosophila Formin Fhod"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Control of Cargo Specificity for Cytoplasmic Dynein"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"How a Short Collection of Treadmilling Tubulin-Like Filaments Control Bacterial Cell Division"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Bidirectional Interactions of Membranes and the Cytoskeleton
7:30 pm - 7:50 pm
"Tuning of Golgi-Derived Microtubule Nucleation on a Scale of Seconds, Minutes, and Days"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Harnessing Actin Dynamics for Endocytic Trafficking"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Direct Coupling of the Actin Cytoskeleton to a Viral Fusogen Drives Cell-Cell Fusion"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Those Mythterious MyTH4 Myosins: Evolutionary Insights Drawn from Comparisons of Their Roles in Amoebae and Mammals"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Actin Effects Across Two Membranes: How the Formin INF2 Stimulates both Inner and Outer Membrane Dynamics During Mitochondrial Fission"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Coordination of Complex Processes by Signaling and the Cytoskeleton
9:00 am - 9:20 am
"Anillin Regulates Epithelial Mechanics by Structuring Junctional and Medial-Apical Actin Networks"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"CARMIL3's Role in Establishing Left-Right Asymmetry During Zebrafish Development"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Actin Stability Promotes Stress Resistance in Morphogenesis"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"The Frog-Killing Chytrid Fungus Is a Naked Amoeba that Can Build a Cell Wall"
10:15 am - 10:20 am
Discussion
10:20 am - 10:40 am
"Supergrowth: Coordination of Cell Growth with Cell Size, Cytoplasmic Density and Turgor Pressure"
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
Coffee Break
11:10 am - 11:20 am
"Optogenetic Regulation of Rho1 in Drosophila "
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Mechanochemical Signaling at the Adherens Junction"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Processive Motility of Multi-Motor Kinesin-14 Teams Underlies Regulation of Microtubule Minus-End Dynamics"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Dynamic Force Patterns Coordinate Cell Movements During Embryonic Wound Repair"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Septum Formation in Fission Yeast Cytokinesis"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Modeling and Measuring Mesoscopic Cytoskeletal Rearrangements in Cytokinesis"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Actin-Like Protein FtsA Self-Organizes to Reshape Membrane Architecture and Remodel the Z-Ring in Escherichia coli "
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"FLIRTing with Cytokinesis: Testing Cell Division Models Using Local Inactivation of Cytokinetic Proteins"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"New Mechanistic Insights About Cytokinesis in Fission Yeast"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Divergent Dynamics and Behaviors of Cytoskeletal Ensembles
9:00 am - 9:20 am
"Torques and Forces in the Mitotic Spindle"
9:20 am - 9:25 am
Discussion
9:25 am - 9:35 am
"The Evolutionary Basis of Microtubule Quaternary Structure"
9:35 am - 9:40 am
Discussion
9:40 am - 10:00 am
"One Centriole for Each Occasion - Centriole Variation in Development, Evolution and Disease"
10:00 am - 10:05 am
Discussion
10:05 am - 10:15 am
"The ESCRT-III Machinery of Cytokinetic Abscission Is Spatio-Temporally and Functionally Linked to Septin GTPases"
10:15 am - 10:20 am
Discussion
10:20 am - 10:40 am
"Reeling in the Cilium: How Chytrid Fungi Rapidly Retract a Long Ciliary Axoneme into the Cell Body"
10:40 am - 10:45 am
Discussion
10:45 am - 11:10 am
Coffee Break
11:10 am - 11:20 am
"Rab27a Co-Ordinates Actin-Dependent Long-Range Organelle Transport by Integrating the Activity of Motors and Track Assembly Proteins"
11:20 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Molecular Insight into Microtubule Nucleation"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
"Design Principles of a Microtubule Polymerase"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Probing ESCRT-III Filament Dynamics at Different Scales"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
On the Mechanisms of Cells Moving and Sitting Still
7:30 pm - 7:50 pm
"A Template for Actin Organization at the Leading Edge"
7:50 pm - 7:55 pm
Discussion
7:55 pm - 8:15 pm
"Intracellular Calcium and Actin Polymerization Are Antagonistic During Polarized Cell Expansion"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:30 pm
"Feedbacks Between ECM Signaling, GTPase Signaling, and Cytoskeletal Remodeling Promote Morphological Heterogeneity Among Motile Cells"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 8:55 pm
"Molecular-Scale Anisotropy and Orientation of Activated Integrins in Focal Adhesions Due to Retrograde Actin Flow"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Cooperation of Nonmuscle Myosin Paralogs in Cell-Wide Organization of the Actin Cytoskeleton"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure