Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Molecular Control of Connectivity |
| Discussion Leaders: Marc Freeman (University of Massachusetts Medical School, USA) and Rosalind Segal (Harvard Medical School / Dana-Farber Cancer Institute, USA) |
7:40 pm - 8:20 pm | Liqun Luo (Stanford University, USA) "Assembly of the Fly Olfactory Circuit and Beyond" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Marc Tessier-Lavigne (Rockefeller University, USA) "Molecular Pathways Regulating Axonal Degeneration" |
9:15 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Patterning the Nervous System |
| Discussion Leader: Claude Desplan (New York University, USA) |
9:00 am - 9:20 am | Jeremy Dasen (New York University School of Medicine, USA) "The Ancient Origins
of Neural Circuits for Land Walking" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Kevin Wright (Vollum Institute, Oregon Health and Science University, USA) "Scaffolding Neural Development with Dystroglycan" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Jeremy Reiter (University of California, San Francisco, USA) "Ciliary Signaling with Hedgehog During Neurogenesis" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Paola Bovolenta (Consejo Superior Investigaciones Cientificas (CSIC) / Universidad Autonoma de Madrid, Spain) "Secreted Frizzled Related Proteins in Forebrain Development" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Gordon Fishell (NYU Langone Medical Center, USA) "Specification and Survival of Inhibitory Interneurons" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:10 pm | Selected from Poster Abstracts: Bulent Ataman (Harvard Medical School, USA) "Evolutionary Repurposing of an Activity-Regulated Factor in Primate Neocortex" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Generating Diversity in Neural Cell Fate and Function |
| Discussion Leader: Liqun Luo (Stanford University, USA) |
7:30 pm - 7:50 pm | Claude Desplan (New York University, USA) "Evolutionary Leaps in Patterning of the Retina" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Corey Harwell (Harvard Medical School, USA) "Mammalian Cortical Diversity and Precision in Wiring" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Fiona Doetsch (University of Basel, Switzerland) "Stem Cell Dynamics in the Adult Brain" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:10 pm | Selected from Poster Abstracts: Jay Bikoff (Columbia University, USA) "Spinal Inhibitory Interneuron Diversity and Position Delineate Variant Motor Microcircuits" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Selected from Poster Abstracts: Daniel Pederick (The University of Adelaide, Australia) "Mosaic Expression of Pcdh19 Causes Segregation of Pcdh19-Wild Type and Pcdh19-Null Neurons in the Developing Mouse Cortex Leading to an Epileptic Phenotype" |
9:25 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Stem Cells in Circuit Assembly and Repair |
| Discussion Leader: Fiona Doetsch (University of Basel, Switzerland) |
9:00 am - 9:20 am | Yukiko Gotoh (University of Tokyo, Japan) "Intrinsic and Extrinsic Regulators of Neural Stem Cells" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Soo-Kyung Lee (Oregon Health and Science University, USA) "miRNAs in Motor Neuron Fate and Differentiation" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Pierre Vanderhaeghen (University of Brussels, Belgium) "From Stem Cells to Neural Networks in the Cerebral Cortex" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:15 am | Simon Hippenmeyer (Institute of Science and Technology Austria, Austria) "Molecular Mechanisms of Neural Stem Cell Lineage Progression" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Mary Hynes (Rockefeller University, USA) "Widespread Differential Expression of Coding Region and 3’ UTR Sequences in Neurons and Other Tissues" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Peri Kurshan (Stanford University, USA) "How Are New Synapses Added to Existing Circuits? Diverse Roles for Two Cell Adhesion Molecules" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Debby Silver (Duke University Medical Center, USA) "Dynamic mRNA Transport and Translation in Neural Stem Cells of the Developing Brain" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Wiring Neural Circuits |
| Discussion Leader: Kelly Monk (Washington University School of Medicine, USA) |
7:30 pm - 7:50 pm | Samuel Pfaff (Howard Hughes Medical Institute / Salk Institute for Biological Studies, USA) "Establishing Connectivity in Locomotor Circuits" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Cagla Eroglu (Duke University Medical Center, USA) "Control of Synapse Formation and Plasticity by Astrocytes" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | David Ginty (Howard Hughes Medical Institute / Harvard Medical School, USA) "The Organization and Development of Light Touch Sensitive Neurons" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Alex Kolodkin (Johns Hopkins School of Medicine / Howard Hughes Medical Institute, USA) "Neuropilin-2/Plexin A3 Regulation of Sema3F-Mediated AMPA Receptor Homeostatic Scaling" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neuron-Glia Interactions During Development |
| Discussion Leader: Cagla Eroglu (Duke University Medical Center, USA) |
9:00 am - 9:20 am | Kelly Monk (Washington University School of Medicine, USA) "Mechanisms of Myelinating Glial Cell Development" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | William Talbot (Stanford University, USA) "Genetic Analysis of Glial Development and Function in Zebrafish" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Shai Shaham (Rockefeller University, USA) "Glial Control of Neuron Receptive Ending Shape
and Function" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:15 am | Michelle Monje (Stanford University, USA) "Adaptive Myelination" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:35 am | Jan Pielage (University of Kaiserslautern, Germany) "Axonal Transport Defects and Neurodegeneration - Cause or Consequence?" |
11:35 am - 11:40 am | Discussion |
11:40 am - 11:55 am | Megan Corty (University of Massachusetts Medical School, USA) "Analysis of Axon Ensheathment" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Simone Mayer (University of California, San Francisco, USA) "A High Throughput Screen in the Developing Human Neocortex Integrates Single-Cell Physiology and Transcriptomics" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Establishing and Maintaining Functional Circuits |
| Discussion Leader: Dorothy Schafer (University of Massachusetts Medical School, USA) |
7:30 pm - 7:50 pm | Pelin Volkan (Duke University, USA) "Stability and Plasticity in the Drosophila Olfactory System Across Timescales" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Luisa Cochella (Research Institute of Molecular Pathology (IMP), Austria) "Roles for miRNAs in Neural Cell Fate and Function" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Marc Hammarlund (Yale University, USA) "Wiring and Re-Wiring the Nervous System of C. elegans" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Nils Brose (Max Planck Institute for Experimental Medicine, Germany) "Neuroligins
at Inhibitory Synapses - From Synapse Formation to Neuropsychiatric Disorders" |
9:20 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Neurite Polarity, Outgrowth, and Survival |
| Discussion Leader: Corey Harwell (Harvard Medical School, USA) |
9:00 am - 9:20 am | Frank Bradke (German Center for Neurodegenerative Diseases, Germany) "Regulation of Axonal Growth in Development and Injury" |
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Shane Liddelow (Stanford University, USA) "What Do Reactive Astrocytes Do?" |
9:50 am - 10:00 am | Discussion |
10:00 am - 10:30 am | Coffee Break |
10:30 am - 10:50 am | Michael Greenberg (Harvard Medical School, USA) "Signaling Networks that Regulate Synapse Development and Cognitive Function" |
10:50 am - 11:00 am | Discussion |
11:00 am - 11:20 am | Claudia Bagni (University of Rome Tor Vergata, Italy / University of Lausanne, Switzerland) "The Multi-Tasking CYFIP1 Protein Orchestrates Brain Wiring and Social Behaviour" |
11:20 am - 11:30 am | Discussion |
11:30 am - 11:50 am | Daniel Colon-Ramos (Yale University, USA) "Synaptic Position Requires Neuronal Autophagy and Glial Instructions" |
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Georgia Rapti (The Rockefeller University, USA) "Glia and Pioneer Neurons Direct Hierarchiacal Assembly of the C. elegans Brain" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Neurodevelopmental Disorders and Pruning |
| Discussion Leader: Alex Kolodkin (Johns Hopkins School of Medicine / Howard Hughes Medical Institute, USA) |
7:30 pm - 7:50 pm | Oren Schuldiner (Weizmann Institute of Science, Israel) "A Systematic Exploration of Neuronal Remodeling Reveals a Transcription Factor Hierarchy" |
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Angelique Bordey (Yale University, USA) "Alterations in Cortical Development in Neurogenetic Disorders" |
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Dorothy Schafer (University of Massachusetts Medical School, USA) "Activity-Dependent Mechanisms of Microglial Synaptic Pruning" |
8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:15 pm | Summer Thyme (Harvard University, USA) "Functional Analysis of Schizophrenia-Associated Genes During Zebrafish Development" |
9:15 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |