Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Sleep Apnea, Oxygen Radicals and Hypertension |
| Discussion Leader: Rakesh Patel (University of Alabama at Birmingham, USA) |
7:40 pm - 7:45 pm | Opening Remarks |
7:45 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:40 pm | Gregg Semenza (Johns Hopkins University, USA) "Sleep Apnea, Oxygen Radicals and Hypertension" |
8:40 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Pathophysiologic Roles of Oxidized Lipids |
| Discussion Leaders: Henry Jay Forman (University of Southern California, USA) and Homero Rubbo (University of the Republic, Uruguay) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:25 am | Bruce Freeman (University of Pittsburgh, USA) "Anti-Inflammatory Electrophilic Fatty Acid Species" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | David Ford (Saint Louis University School of Medicine, USA) "Chlorinated Fatty Acids and ROS" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Anna-Liisa Levonen (University of Eastern Finland, Finland) "Activation of Stress Signaling Pathways by Electrophilic Lipids" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:25 am | Valerie O'Donnell (Cardiff University, United Kingdom) "Mapping the Platelet Oxy-Lipidome" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Chris Cooper (University of Essex, United Kingdom) "Artificial Blood: Engineering a Haemoglobin Based Oxygen Carrier with Decreased Lipid Peroxidation Activity" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:15 pm | Selected from Poster Abstracts: Witold Korytowski (Medical College of Wisconsin, USA) "Impairment of Macrophage Cholesterol Efflux by Cholesterol Hydroperoxide Trafficking; Implications for Atherogemesis Under Oxidative Stress" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Sirtuins, Aging and Redox |
| Discussion Leaders: Rick Domann (University of Iowa, USA) and Sruti Shiva (University of Pittsburgh, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:45 pm | Selected from Poster Abstracts: Lindsey Gano (University of Colorado Anschutz Medical Campus, USA) "SIRT3 Dysfunction in Experimental Temporal Lobe Epilepsy" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:10 pm | Raul Mostoslavsky (Massachusetts General Hospital, Harvard Medical School, USA) "Sirtuins in Regulation of Redox Status" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:40 pm | Carlos Escande (Institut Pasteur de Montevideo, Uruguay) "Role of the Protein DBC1 in the Regulation of Obesity and Aging" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:10 pm | Paul Brookes (University of Rochester Medical Center, USA) "Sirtuins and Mitochondrial Redox" |
9:10 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Emerging Paradigms in Redox Signaling |
| Discussion Leaders: Victor Darley-Usmar (University of Alabama at Birmingham, USA) and Douglas Thomas (University of Illinois at Chicago, USA) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:25 am | Raj Soorappan (University of Alabama at Birmingham, USA) "Reductive Stress and Proteotoxicity" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Tobias Dick (German Cancer Research Center, Germany) "Thiol Peroxidase Based Redox Relays" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Yvonne Hanssen Heininger (University of Vermont, USA) "Glutaredoxin and S-Glutathionylation Dependent Redox Signaling" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:25 am | Daniela Salvemini (St. Louis University, USA) "Free Radicals and Pain Sensing" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Joris Messens (VIB, Vrije Universiteit Brussel, Belgium) "Promiscuity in Thiol Redox Control" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:15 pm | Selected from Poster Abstracts: Shireen Attaran (University of Pittsburgh, USA) "Prdx1 Inhibits Breast Cancer Progression Through Inhibiting the Activated Phenotype of Mammary Stroma-Associated Fibroblasts" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | New Detection Methods and Probes for Reactive Species |
| Discussion Leaders: Paul Winyard (University of Exeter Medical School, United Kingdom) and Jacek Zielonka (Medical College of Wisconsin, USA) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:55 pm | Vinayak Gupta (The Scripps Research Institute - Florida, USA) "Tag-Switch Methods for Thiols and Sulfide Measurement" |
7:55 pm - 8:05 pm | Discussion |
8:05 pm - 8:25 pm | Dan Yang (The University of Hong Kong, Hong Kong SAR China) "Fluorescent Probe Based Detection of Free Radicals in Biological Systems" |
8:25 pm - 8:35 pm | Discussion |
8:35 pm - 8:55 pm | Cristina Furdui (Wake Forest School of Medicine, USA) "Chemical Approaches to Investigate Thiol-Based Redox Regulation in Biological Systems" |
8:55 pm - 9:05 pm | Discussion |
9:05 pm - 9:20 pm | Ashutosh Kumar (National Institute of Environmental Health Sciences, NIH, USA) "Immuno-Spin Trapping of Alpha-Synuclein Radical Formed in Maneb and Paraquat Induced Model of Parkinson's Disease" |
9:20 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Oxygen Radicals and Mechanisms of Disease |
| Discussion Leader: Victor Thannickal (University of Alabama at Birmingham, USA) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:25 am | Karen Bernard (University of Alabama at Birmingham, USA) "Mitochondrial ROS and Lung Fibrosis" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Carola Neumann (Magee-Womens Research Institute, USA) "The Role of Prx-1 in Cancer Signaling" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Francisco Laurindo (Heart Institute of the University of São Paulo, Brazil) "Pathophysiology of NOX in Cardiovascular Disease" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:25 am | Douglas Spitz (University of Iowa, USA) "ROS and Cancer" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Manisha Patel (University of Colorado, Anschutz Medical Campus, USA) "Mitochondrial ROS and Neuronal Disorders" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:15 pm | Selected from Poster Abstracts: Clare Hawkins (Heart Research Institute, Australia) "Role of the Myeloperoxidase Oxidant Hypothiocyanous Acid (HOSCN) in Redox Perturbation and Cellular Dysfunction" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Infectious Diseases and Free Radicals |
| Discussion Leaders: Michael Davies (University of Copenhagen, Denmark) and Christine Winterbourn (University of Otago Christchurch, New Zealand) |
7:30 pm - 7:35 pm | Introduction by Discussion Leader |
7:35 pm - 7:45 pm | Selected from Poster Abstracts: Lin Mantell (North Shore University Hospital, St. John's University, USA) "The α7 Nicotinic Acetylcholine Receptor Agonist GTS-21 Improves Bacterial Clearance by Restoring Hyperoxia-Compromised Macrophage Function" |
7:45 pm - 7:50 pm | Discussion |
7:50 pm - 8:10 pm | Jon Lundberg (Karolinska Institutet, Sweden) "Gut Microbiota and Nitrogen Oxide Signaling" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:40 pm | Michelle Reniere (University of Washington, USA) "Glutathione and Pathogen Virulence" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:10 pm | Lars Dietrich (Columbia University, USA) "Redox Regulation of Biofilm Development in Pseudomonas aeruginosa" |
9:10 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Role for CO and H2S in Oxygen Radicals Biology |
| Discussion Leaders: Neil Hogg (Medical College of Wisconsin, USA) and Jon Lundberg (Karolinska Institutet, Sweden) |
9:00 am - 9:05 am | Introduction by Discussion Leader |
9:05 am - 9:25 am | Beatriz Alvarez (University of the Republic, Uruguay) "Reactivity of Hydrogen Sulfide with Oxidants" |
9:25 am - 9:35 am | Discussion |
9:35 am - 9:55 am | Wayne Orr (LSU Health Sciences Center Shreveport, USA) "H2S and ROS Signaling" |
9:55 am - 10:05 am | Discussion |
10:05 am - 10:25 am | Takaaki Akaike (Tohoku University Graduate School of Medicine, Japan) "Polysulfides and Redox Signaling" |
10:25 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:25 am | Roland Stocker (Victor Chang Cardiac Research Institute, Australia) "Novel Insights into Tryptophan Oxidation Mediated by Indoleamine 2,3-Dioxygenase and Its Role in Arterial Relaxation" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Roberto Motterlini (INSERM U955 / Université Paris-Est, France) "CO-Releasing Molecules and Redox Signaling" |
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:15 pm | Selected from Poster Abstracts: Bindu Paul (Johns Hopkins University School of Medicine, USA) "The Intersection Between H2S and Superoxide Signaling in Amyotrophic Lateral Sclerosis" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session: Mitochondrially Targeted Antioxidants and Signaling |
| Discussion Leader: Ana Denicola (University of the Republic, Uruguay) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:30 pm | Michael Murphy (MRC Mitochondrial Biology Unit, United Kingdom) "Mitochondrially Targeted Antioxidants and Signaling" |
8:30 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | General Discussion |
9:20 pm - 9:30 pm | Closing Remarks |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |