SUNDAY |
2:00 pm - 11:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GAMETE MATURATION AND FERTILIZATION |
7:30 pm - 7:35 pm | Welcome |
7:35 pm - 7:45 pm | Discussion Leader: Richard Schultz (University of Pennsylvania)
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7:45 pm - 8:10 pm | Teresa Woodruff (Northwestern University) "Making and managing follicles" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | John Eppig (The Jackson Laboratory) "Oo-outsourcing of oocyte-deficient metabolic functions" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:10 pm | Robert Braun (University of Washington School of Medicine) "Androgen receptor function in testis somatic cells" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | Short Selected Talk: Nikolay Spiridonov (U.S. FDA) "Mammalian protein kinase SSTK essential for male fertility" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STEM CELLS: FROM GAMETES TO EMBRYOS AND BEYOND |
9:00 am - 9:15 am | Discussion Leader: Peter Donovan (University of California, Irvine) |
9:15 am - 9:40 am | Erika Matunis (Johns Hopkins University) "Mechanisms of stem cell renewal in the Drosophila testis" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:00 am | Short Selected Talk: April Pyle (Johns Hopkins University) "Human embryonic stem cell survival factors" |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Haifan Lin (Duke University) "Self-renewing mechanisms of stem cells in the germline" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Janet Rossant (The Hospital for Sick Children) "Lineage commitment in the mouse blastocyst" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Takashi Shinohara (Kyoto University) "Culture and genetic modification of mouse germline stem (GS) cells" |
11:55 am - 12:00 pm | Discussion |
12:15 pm | Group Photo |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GENE REGULATION DURING GAMETOGENESIS AND EMBRYOGENESIS |
7:30 pm - 7:45 pm | Discussion Leader: Mitch Eddy (NIEHS) |
7:45 pm - 8:10 pm | Michelle Carmell (Cold Spring Harbor Laboratory) "A germline-specific class of small RNAs binds mammalian Piwi proteins" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Kami Ahmad (Harvard Medical School) "Essential Functions of the H3.3 histone variant in Drosophila" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:00 pm | Short Selected Talk: Daniel Arnold (McGill University) "Maternal stem-loop binding protein is essential for early embryonic development in the mouse" |
9:00 pm - 9:25 pm | Miles Wilkinson (U. T. M. D. Anderson Cancer Center) "The Rhox homeobox gene cluster" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MEIOSIS |
9:00 am - 9:15 am | Discussion Leader: Paula Cohen (Cornell University) |
9:15 am - 9:40 am | Paula Cohen (Cornell University) "The complexities of mismtach repair pathways in mammalian meiosis and gametogenesis" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Mary Herbert (Newcastle Fertility Centre) "Spindle checkpoint function in mammalian oocytes" |
10:10 am - 10:15 am | Discussion |
10:15 am - 10:30 am | Short Selected Talk: Alexandra Reis (University of Newcastle) "Female first meiosis requires separase-dependent inactivation of cyclin-dependent kinase 1" |
10:30 am | Coffee Break |
11:00 am - 11:25 am | Laurinda Jaffe (University of Connecticut Health Center) "Regulation of meiotic prophase arrest in mammalian oocytes by a G protein coupled receptor" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | James Turner (MRC National Institute for Medical Research) "Silencing of unpaired meiotic DNA and its influence on late spermatogenic gene expression" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Selected Talk: Satoshi Namekawa (Massachusetts General Hospital) "Post-meiotic sex chromatin in the male germline of mice" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | THE ART AND SCIENCE OF ASSISTED REPRODUCTION |
7:30 pm - 7: 40 pm | Discussion Leader: Catherine Racowsky (Brigham and Women’s Hospital) |
7:40 pm - 7:55 pm | Catherine Racowsky (Brigham and Women’s Hospital) "Embryo selection in clinical ART" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Ann Thurin Kjellberg (Sahlgrenska Academy) "Elective single embryo transfer; the Swedish experience" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Mary Croughan (University of California, San Francisco) "Childhood outcomes following infertility and infertility Treatment" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | John McCarrey (University of Texas at San Antonio, Texas) "Assessment of genetic integrity in mouse embryos produced by assisted reproductive technologies or cloning" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | EPIGENETIC REGULATION OF THE GERMLINE AND EARLY EMBRYO |
9:00 am - 9:15 am | Discussion Leader: Tamara Davis (Bryn Mawr College) |
9:15 am - 9:40 am | Wolf Reik (The Babraham Institute) "Epigenetic regulation of imprinting and genome reprogramming" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:00 am | Short Selected Talk: Kazuhiro Iwahashi (University of Hawaii) "Assessment of sex-specific epigenetic reprogramming in murine germ cells cultured in vitro" |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Scott Coonrod (Weill Medical College of Cornell University) "Epigenetic reprogramming in the murine egg and early embryo" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Deborah Bourc’his (Institut Jacque Monod) "Retrotransposon regulation and processing during mammalian spermatogenesis" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:55 am | Emma Whitelaw (University of Sidney) "An ENU screen for genes involved in epigenetic reprogramming" |
11:55 am - 12:00 pm | Discussion |
12:00 pm - 12:15 pm | Short Selected Talk: Jason Knott (Serono Research Institute) "Search for epigenetic markers of embryo quality: Elucidation of the role of brg1 during preimplantation development in the mouse" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | ENVIRONMENTAL IMPACTS ON EMBRYOGENESIS AND GAMETE PROGRAMMING |
7:30 pm - 7:45 pm | Discussion Leader: Michael Skinner (Washington State University) |
7:45 pm - 8:10 pm | Pat Hunt (Washington State University) "Can environmental exposures impact the genetic quality of our gametes?" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Matthew Anway (Washington State University) "Epigenetic transgenerational actions of endocrine disruptors on gamete programming: new paradigm for disease etiology" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:10 pm | Cheryl Walker (UT MD Anderson Cancer Center) "Developmental programming of tumor suppressor gene penetrance by environmental estrogens" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:30 pm | Short Selected Talk: Shoukhrat Mitalipov (Oregon National Primate Research Center) "Nuclear remodeling and reprogramming following somatic cell nuclear transfer in nonhuman primates" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | GENETICS, GENOMICS, PROTEOMICS AND NEW TECHNOLOGY |
9:00 am - 9:15 am | Discussion Leader: Mary Ann Handel (The Jackson Laboratory) |
9:15 am - 9:40 am | Mary Ann Handel (The Jackson Laboratory) "Mutagenesis: an unbiased approach for identification of novel genes required for gametogenesis" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:00 am | Short Selected Talk: Ina Dobrinski (University of Pennsylvania) "Building a testis - formation of functional testis tissue after transplantation of isolated cells" |
10:00 am | Coffee Break |
10:30 am - 10:55 am | Gregory Kopf (Wyeth Research) "Utilizing genomics and proteomics to identify therapeutic targets and expand our knowledge base in reproductive biology" |
10:55 am - 11:00 am | Discussion |
11:00 am - 11:25 am | Eric Schadt (Rosetta Inpharmatics) "Leveraging DNA and gene expression data from multiple tissues in mammalian populations to reconstruct gene networks associated with disease" |
11:25 am - 11:30 am | Discussion |
11:30 am - 11:45 am | Short Selected Talk: David Miller (University of Leeds) "Chromatin partitioning in human and murine spermatozoa" |
11:45 am - 12:00 pm | Short Selected Talk: Christopher Oakes (McGill University) "A Unique Configuration of Chromosomal DNA Methylation Patterns in the Testis" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | FOUNDERS’ FORUM |
| Discussion Leader: Marisa Bartolomei (University of Pennsylvania School of Medicine) |
7:30 pm - 8:00 pm | Rudolf Jaenisch (Whitehead Institute for Biomedical Research) "Nuclear reprogramming and pluripotency" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Davor Solter (Max-Planck Institute of Immunobiology) "Epigenetic control of early mammalian development" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | John Biggers (Harvard Medical School) "Media: The environment of the preimplantation embryo in vitro" |
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |