|9:00 am - 12:30 pm||Advances In Membrane Biology Derived from Red Cell Studies|
|Discussion Leader: Vann Bennett, Duke Univ.|
|Ronald R. Dubreuil, University of Chicago, IL|
"A molecular and genetic approach to the membrane skeleton in Drosophila"
|William James Nelson, Stanford Univ. School of Medicine, Stanford, CA|
"Localization of a spectrin isoform in the golgi complex of non-erythroid cells"
|Anthony P. Bretscher, Cornell University, Ithaca, NY|
"Ezrin and moesin in the cortical cytoskeleton of non-muscle cells"
|Carol Gregorio, The Scripps Research Institute, La Jolla, CA|
"Tropomodulin: an actin filament regulatory protein in red cells and muscle"
|Vann Bennett and Stephen Lambert, Howard Hughes Medical Institute, Duke University Medical Center, Durham, NO |
"Ankyrins and specialized cell domains in the nervous system"
|LuAnne Peters, Children's Hospital, Boston, MA|
"Cloning, sequencing, chromosomal localization and tissue distribution of an axonal and epithelial ankyrin, Ank-3, in the mouse"
|7:30 pm - 9:30 pm||Globin Gene Regulation|
|Discussion Leader: Frank Grosveld, Erasmus Univ.|
|Frank Grosveld, Erasmus University, Rotterdam, Holland|
"β-globin regulation by the LCR"
|George Stamatoyannopoulos, Univ. of Washington, Seattle|
"Developmental Control of Human Globin Genes"
|Mark Groudine, Hutchinson Cancer Center, Seattle, WA|
"The human β-globin LCR"
|Margaret Baron, Harvard University, Cambridge, MA |
"Regulation of the human embryonic β-globin gene is mediated by synergistic interactions among multiple DNA elements"
|9:00 am - 12:30 pm||Erythroid Transcription Factors|
|Discussion Leader: Stuart Orkin, Harvard Univ. Med|
|Gary Felsenfeld, NIH, Bethesda, MD|
"Chromatin structure and the regulation of globin gene expression"
|Beverly Emerson, Salk Institute, La Jolla, CA|
"Developmental regulation of β-globin transcription in vitro"
|Stuart Orkin, Hughes Medical Institute, Boston, MA|
"New insights into the roles of GATA-1 and GATA-2"
|Paul-Henri Romeo, Hopital Henri Mondor, Paris, France|
"Studies of erythroid gene expression"
|Stephen Jane, NIH, Bethesda, MD|
"New mechanisms for γ-globin gene regulation"
|James J. Bieker, Mount Sinai School of Medicine, New York, NY|
"Molecular analyses of EKLF, an erythroid specific transcription factor"
|7:30 pm - 9:30 pm||Molecular Basis of Membrane Transport|
|Discussion Leader: Jerry Lingrel, Univ. of Cincinnati School of Med.|
|Ron Kopito, Stanford University, Stanford, CA|
"Plasma membrane anion exchangers"
|Michael L. Jennings, Univ. of Texas Med. Branch, Galveston, TX|
"Structure-function relations in the human red cell anion transporter"
|Mike M. Muekler, Washington Univ. School of Medicine, St. Louis, MO|
"The Glut1 and Glut4 glucose transporters"
|9:00 am - 12:30 pm||Non-Globin Gene Expression|
|Discussion Leader: Bernard G. Forget,Yale Univ. School of Med.|
|Jane E. Barker, The Jackson Laboratory, Bar Harbor, ME|
"Different ankyrin and β-spectrin isoforms in the mouse"
|Edward J. Benz, University of Pittsburgh, School of Medicine, Pittsburgh, PA|
"Genomic structure and regulated splicing of protein 4.1 gene"
|John G. Conboy, Lawrence Berkeley Lab, Berkeley, CA|
"Changes in protein 4.1 structure and function during erythroid differentiation, mediated by alternative splicing"
|Jean Delaunay, Faculte de Medecine Grange-Blanche, Lyon, France|
"Allele αLELY, a low expression allele of the α-spectrin gene: Possible impairment of the spectrin dimer nucleation site"
|John Winkelmann, Univ. of Minnesota Medical School, Minneapolis, MN|
"Alternative splicing of the human erythrold β-spectrin gene"
|7:30 pm - 9:30 pm||Embryogenesis|
|Discussion Leader: Doug Melton, Harvard Univ.|
|Gordon Keller, National Jewish Hospital, Denver, CO|
"Hematopoietic development of embryonic stem cells in culture"
|Doug Melton, Harvard University, Cambridge, MA|
"Induction of globin gene expression and mesoderm in Xenopus"
|Roger Patient, King's College, London, UK|
"Expression of GATA-2 is an early marker for blood"
|Leonard I. Zon, Children's Hospital, Boston, MA|
"Induction of hematopoiesis during Xenopus embryogenesis"
|9:00 am - 12:30 pm||Red Cell Structural Proteins and Membrane Integrity|
|Discussion Leader: Mohandas Narla, Lawrence Berkeley Lab.|
|Philip S. Low, Purdue University, West Lafayette, IN|
"Regulation of interactions between band 3 and tyrosine kinases"
|Athar H. Chishti, St. Elizabeth Hospital, Boston, MA|
"Dematin and P55: two novel components of erythroid junctional complex"
|Mike Tanner, University of Bristol, Bristol, UK|
"Associations and structure of red cell band 3"
|7:30 pm - 9:30 pm||Selected Posters|
|Discussion Leader: Peter Agre, Johns Hopkins|
|(selected poster presentations)|
|9:00 am - 12:30 pm||Erythropoiesis / Hematopoiesis|
|Discussion Leader: David A. Williams, Indiana Univ.|
|Hartmut Beug, Research Institute for Molecular Pathology, Vienna, Austria|
"Self-renewing red cell progenitors: Induction by cooperating nuclear hormone receptors and tyrosine kinases"
|Stanford B. Krantz, Vanderbilt University|
"Use of highly purified human erythroid progenitor cells to determine specific growth factor requirements and cytokine effects"
|Sandra Ruscetti, NCI|
"Transactivation of erythroid specific gene by a myb/ets-containing retrovirus"
|David A. Williams, Howard Hughes Medical Institute, Herman B. Wells Center for Pediatric Research, Indiana Univ. School of Med.|
"Molecular characterization of stromal-derived growth factors IL-11 and Steel factor"
|Neal Young, NIH|
"Molecular and cellular basis for B19 erythroid tropism"