Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Vaccines, Treatment and Resistance
7:40 pm - 7:55 pm
Introduction by Discussion Leader
7:55 pm - 8:20 pm
"Mechanisms of Salmonella typhi Virulence"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"An Atlas of Human Genetic Variation Affecting Host-Pathogen Traits Reveals Regulatory Variants Modulating Salmonella Invasion and Typhoid Fever Risk"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:10 pm
"Vaccines Against Nontyphoidal Salmonella: The Case, the Candidates and the Pathway Forward"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Molecular Mechanisms of Virulence
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Sweet Interaction: A Key Determinant of Typhoid Toxin's Host and Tissue Tropism"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Emerging Salmonella enterica Serovar Infantis Induces a Strong Pro-Inflammatory Response that Is Dependent on the pESI Virulence Plasmid"
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Metabolite Signaling Influences Salmonella Systemic Infection"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"High-Throughput Screening of Type III Secretion Determinants"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
"When the Former Is Exploited by the Latter"
11:50 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Suppression of the Adaptive Immune Response"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Controlling Host-Membrane Trafficking to Establish Systemic Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Visualization of Salmonella -Induced Filaments Through Site-Specific Fluorescent Labeling of SPI-2 SifA Effector Protein"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Colonization of the Epithelial Cell Cytosol by Salmonella "
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Interactions of Salmonella with Host Cells Through the SP1-T3SS"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Innate Immune Response
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Sensing of Salmonella by Noncanonical Inflammasomes"
9:30 am - 9:40 am
Discussion
9:40 am - 10:05 am
"Pattern Recognition Receptor Redundancy Converges on Cell Death"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Paneth Cells Secrete Lysozyme via Secretory Autophagy During Bacterial Infection of the Intestine"
10:25 am - 10:30 am
Discussion
10:30 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Innate Immune Inhibition by Salmonella Effector Proteins"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"The Bacterial Amyloid Curli: Expression, Immune Recognition and Pathogenesis"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Intracellular Salmonella and the Second Messenger c-di-GMP"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metabolism and Pathogenesis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Interaction of Salmonella typhimurium with the Gut Microbiota"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Microbiota-Derived Aspartate Drives Salmonella Expansion During Colitis"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:50 pm
"The Interplay of Bacterial Pathogens, Host Metabolites and Immune Factors in the Ecosystem of the Mammalian Gut"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Metabolic Adaptations to Oxidative Stress in Salmonella Pathogenesis"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"The Interplay Between Bacterial Genetics and Intestinal Colonization"
9:35 am - 9:45 am
Discussion
9:45 am - 9:55 am
"RHS-Elements Function as Type II Toxin-Antitoxin Modules that Regulate Intra-Macrophage Replication of Salmonella "
9:55 am - 10:00 am
Discussion
10:00 am - 10:25 am
"Regulation of the SPI1 Type Three Secretion System"
10:25 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"The Type III Secretion Signal: Finally an Answer"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
"Salmonella Expresses Horizontally Acquired Genes by Degrading Their Silencer"
11:50 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Antibiotic Tolerant Salmonella During Infection"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Effective Protective Memory Responses to Salmonella Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Salmonella Lipid Homeostasis for Survival and Adaptation Within Host Tissues"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Role of Inflammatory Monocytes in Salmonella Pathogenesis"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"T-Cell Specificity and the Development of Immunity in the Murine Model of Invasive Salmonellosis"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Complex Microbe-Host Interactions
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:35 am
"Infection of Organoids with Salmonella"
9:35 am - 9:45 am
Discussion
9:45 am - 10:10 am
"The Host-Pathogen Interface During Salmonella Chronic Carriage"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:15 am
"Salmonella Single-Cell Biology During Infection: Subsets, Fates and Overall Impact on Disease Progression"
11:15 am - 11:25 am
Discussion
11:25 am - 11:45 am
"Prepared for Every Eventuality: The Microbiota Blocks Salmonella Infection at Different Stages"
11:45 am - 11:55 am
Discussion
11:55 am - 12:20 pm
"Molecular Pathogenesis of Salmonella Diarrhea"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:05 pm
"How Has African Salmonella Become So Dangerous?"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Salmonella Microevolution: Mechanisms and Consequences"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Endogenous Enterobacteriaceae Underlie Variation in Susceptibility to Salmonella Infection"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure