Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: What Human Genetics Can Teach Us About Sleep
7:40 pm - 7:55 pm
Opening Remarks
7:55 pm - 8:50 pm
"What Can Human Genetics Teach us About Sleep"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Paradoxical Somato-Dendritic Decoupling Supports Cortical Plasticity During REM Sleep"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Activity-Dependent Neuronal Tagging to Reveal Sleep's Circuitry and Function
9:00 am - 9:30 am
"Optogenetic-Assisted Circuit Mapping of Sleep Circuits"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Synaptic Tagging to Identify Sleep Circuits"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Cell-Type Specific Control of Rhythms"
11:20 am - 11:30 am
Discussion
11:30 am - 12:00 pm
"Daily Normalization of E/I-ratio by Light-Driven Transcription Maintains Visual Processing"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Functional Analysis of Sleep Circuitry and its Impact on Global Brain Dynamics
6:00 pm - 6:20 pm
"Modeling Sleep Wake Circuits"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Circuit-Specific Flickering of Sleep and Wake Predicts Natural Behaviors"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"New Insights into Sleep Regulation in Flies"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Genetic Dissection of Sleep Homeostasis in Zebrafish"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Metabolic Drivers of the Sleep-Wake Cycle
9:00 am - 9:30 am
"Biophysical Mechanisms for Balancing Sleep Need and Sleep"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Knockdown of GABAA Alpha3 Subunits on Thalamic Reticular Neurons Enhances Deep Sleep in Mice"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:10 am
"Polyamine Elevation and Nitrogen Stress are Toxic Hallmarks of Chronic Sleep Loss in Drosophila Melanogaster"
11:10 am - 11:20 am
Discussion
11:20 am - 11:50 am
"Sleep and Oxidative Metabolites"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Essential Role of the Transcription Factor MEF2C in the Genomic Sleep Loss Response"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Impact of Sleep During Development on Mental Health
6:00 pm - 6:30 pm
"Mechanisms Underlying Sleep Problems in the Autism Spectrum"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"The Role of Development on Normal Sleep"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"The CHD8/CHD7/Kismet Family Links Blood-Brain Barrier Glia and Serotonin to ASD-Associated Sleep Defects"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Sleep and the Regulation of Positive and Negative Emotions
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:40 am
"The Emotional Brain in a Sleepless World"
9:40 am - 9:50 am
Discussion
9:50 am - 10:20 am
"Neural Circuits Underlying Sleep and Emotional Regulation"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Orienting Eye Movements During REM Sleep"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Generating Sleep Oscillations Using Primary Thalamo-Cortical Co-Cultures"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Sleep Duration and Sleep Homeostasis in Birds is Strongly Dependent on Season and Moon Phase"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Heterogeneous Roles for Gap Junctions in Sleep Regulation
6:00 pm - 6:30 pm
"The Role of the Blood-Brain Barrier in Sleep"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"Gap Junctions and other Evolutionarily Conserved Sleep Regulators"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Amino-Acid Transport and Sleep/Wake Regulation"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Systems Approaches for Studying Sleep in Neurodegeneration
9:00 am - 9:30 am
"Sleep, AD and the Human Brain Transcriptome"
9:30 am - 9:40 am
Discussion
9:40 am - 10:10 am
"Sleep, Cognitive Performance and Underlying Neuroanatomical Networks"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
"Sleep Disorders and Alzheimer's Disease"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Proteostasis, Sleep, and Cognitive Behavior in Aging and Alzheimer’s Disease Models"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Familial Natural Short Sleep Mutations Reduce Alzheimer Pathology in Mice"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Sleep and Brain Function: Genetic Insights
6:00 pm - 6:30 pm
"Heritability of Sleep Neurophysiology"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:10 pm
"A Medullary Hub for Controlling REM Sleep and Pontine Waves"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:50 pm
"Circadian Programming of the Ellipsoid Body Sleep Homeostat in Drosophila"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure