Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
The Leading Edge: Emerging Themes in Streptococcal Research
7:40 pm - 8:10 pm
"Coordination of DNA Replication with Cell Division in Streptococcus pneumoniae "
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:50 pm
"Chemical Dissection of Enterococcus faecium Protection Mechanisms"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Immunology of Group A Streptococcus Tonsillitis"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Streptococcal Manipulation of Macrophage and Neutrophil Function
9:00 am - 9:25 am
"Intracellular Replication of Streptococcus pneumoniae Within the Heart"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Pneumococcal Interactions with the Host"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:05 am
"Placental Macrophages Release Macrophage Extracellular Traps and Matrix Metalloproteinases in Response to Streptococcus agalactiae Infection"
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Bacterial Manipulation of Hyaluronan Size as a Strategy for Immune Evasion"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Cyclic di-AMP in GBS Physiology and Host-Pathogen Interaction"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Streptococcal Pathogens Engage Human CEACAM1 Receptor"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Immune Responses to Streptococcal Infection: A Balancing Act
7:30 pm - 7:55 pm
"Strategies Used by Streptococcus suis to Defy the Host Adaptive Immune Response"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Skewed Macrophage Phenotypes in Streptococcal Necrotizing Soft Tissue Infections"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Enrichment of Antigen-Specific Class-Switched B-Cells from Individuals Naturally Immunized by Infection with Group A Streptococcus"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:05 pm
"Type I and Type III Interferons Inhibit Bacterial Clearance Following Influenza Virus Infection"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"C4BP-Mediated Complement Evasion in Streptococcal Infections: How the Good Guys Turn Bad"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Finding a Niche: Streptococcal Colonization of Host Mucosal Barriers
9:00 am - 9:25 am
"Tale of Two Phenotypes: Group A Streptococcal Mechanisms to Persist in the Absence of Symptoms"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Probing the Influence of Salivary Mucins on Oral Streptococci Physiology"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:05 am
"Transmission of the Pneumococcus"
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Competitive Advantage of Streptococcus gallolyticus in Colon Cancer Microbiota"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Multiple Serine Rich Repeat Proteins of Streptococcus oralis : Roles in Surface Fibril Formation, Adhesion and Pathogenesis"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Transcriptional Profiles of Streptococcus pneumoniae Adapted to the Lung Environment"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Polymicrobial Interactions: Life Among the Microbiome
7:30 pm - 8:00 pm
"Mechanisms of Synergy During Enterococcal Polymicrobial Infection"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Biogeography of In Vivo Polymicrobial Biofilms"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Enterococcal-Bacteriophage Interactions Reveal Mechanisms of Phage Resistance and Community Behaviour"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"New Insights into Influenza-Pneumococcal Synergy"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Paradigms in Streptococcal Virulence Factor Action
9:00 am - 9:25 am
"Group A Streptococcus Fuels the Fire"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Importance of Polyenes for GBS Hemolysis"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Group Photo / Coffee Break
10:40 am - 11:05 am
"Molecular Correlates of Nasopharyngeal Infection by Streptococcus pyogenes "
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"Biomimetic Nanoparticles for Broad-Spectrum Antivirulence Therapy"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"A Novel Interaction Between C4BP and the Enn Protein of Group A Streptococcus "
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Early Extracellular Long-Distance Lymphatic Metastasis Is a Route of Systemic Invasion for Virulent Streptococcus pyogenes "
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Streptococci and the Nervous System
5:30 pm - 5:55 pm
"Bacterial Communication with the Brain"
5:55 pm - 6:05 pm
Discussion
6:05 pm - 6:30 pm
"Pain and Neuro-Immune Regulation of Streptococcal Host Defense"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 6:50 pm
"The Group B Streptococcal Adhesin BspC Interacts with Vimentin to Promote Meningitis"
6:50 pm - 6:55 pm
Discussion
6:55 pm - 7:05 pm
"A Comparative Transcriptome Analysis of Human and Porcine Choroid Plexus Cells Infected with Streptococcus suis "
7:05 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
"Role of Stochastic Pneumolysin Expression in Pneumococcal Trafficking Across Host Barriers"
7:25 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
"Streptococcomics": Big Data Approaches to Streptococcal Pathogens
9:00 am - 9:25 am
"Structural Proteomics in Host-Bacterial Interactions"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Defining Streptococcus equi Gene Essentiality in a Susceptible Natural Host"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:05 am
"Dissecting Fitness at the Host-Streptococcal Interface"
11:05 am - 11:15 am
Discussion
11:15 am - 11:40 am
"China Scarlet Fever Outbreak: From Genomics to Function"
11:40 am - 11:50 am
Discussion
11:50 am - 12:05 pm
"Deciphering Streptococcus pneumoniae -Host Interactions Considering the Pathogen's Large Pan-Genome"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Divergence Within Genotypes of Streptococcus pyogenes : A Comparison of UK and USA Genome Sequence Data"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Young Investigator Presentations
7:30 pm - 7:40 pm
"MUC1 Protects Against Severe Streptococcus pneumoniae Infection"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"A Couterselectable Sucrose Sensitivity Cassette Enhances Targeted Mutagenesis in Group B Streptococcus "
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A GAS Quorum-Sensing System Enhances Oropharyngeal Colonization and Resistance to Host Factors via Alterations of the Bacterial Cell Surface"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"A ZIP Family Protein Contributes to Infective Endocarditis Virulence in Streptococcus sanguinis "
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Streptococcus pyogenes Evades Adaptive Immunity Through Specific Modification of Host IgG Glycosylation"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"The Pneumococcal Surface Protease HtrA Contributes to Enhances Bacterial Burden During Influenza/Pneumococcal Confection"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Phase Variation in Streptococcus suis "
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Characterization of a Novel Toxin-Antitoxin System from Streptococcus Progenies"
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure