Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Late-Breaking Topics: Rapid Transmission of Synaptic Ideas
This session is designed to bring all the participants together in a rapid set of poster introductions – 1 slide per person on Sunday evening. This rapid format is highly engaging and geared to alert all conferees to posters that will be presented by non-speakers at the meeting. The vice chair will receive 1 slide of the key point of a poster at least 4 days prior to the meeting so as to compose a continuous presentation allowing about 2 minutes per speaker.
7:40 pm - 9:30 pm
Poster Previews
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Dynamic Regulation of Synaptic Transmission by Protein Turnover and Signaling to the Nucleus
9:00 am - 9:20 am
"Single Synaptic Vesicle Exo-Endocytosis Coupling"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Molecular Organization of Synaptic Protein Turnover"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:50 am
"Synaptic Activity-Dependent Regulation of Transcription"
10:50 am - 11:00 am
Discussion
11:00 am - 11:20 am
"Dynamic Nanoscale Organization of AMPA Receptors and Synaptic Plasticity"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Synapse-to-Nucleus Communication Through NFAT Is Mediated by Rapid L-Type Ca2+ Channel-Dependent Electrochemical Signaling to the Soma"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Communication Between Synapses and the Genome"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Resource Management and Synaptic Plasticity
7:30 pm - 7:50 pm
"How Mitochondria Get to the Synapse and Support Function"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Structural Correlates of Transmitter Release and Readily Releasable Vesicle Pool at Hippocampal Mossy Fiber Synapses"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Life at Low Molecule Number"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Bi-Directional Regulation of the Balance Between Memory Discrimination and Generalization by Functionally Distinct Neuronal Ensembles Within the Memory Engram"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Synaptic Molecular Mechanisms of Critical Period in Memory Formation During Early Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Bidirectional Regulation of Presynaptic Release and Postsynaptic Response
9:00 am - 9:20 am
"Retrograde Homeostatic Trans-Synaptic Signaling"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"O-GlucNAcylation Depresses Excitatory and Inhibitory Transmission in Area CA1 and Dampens Hyperexcitabity via Targeting GluA2 AMPARs"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Post-Translational Palmitoylation and Its Regulation of Synapse Plasticity"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Cell-Autonomous Regulation of Synaptic NMDA Receptors by Postsynaptic Serine Racemase"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Molecular Machinery to Control Synaptic Transmission"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Presynaptic Population Activity in the Cerebellar Cortex During Locomotion"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Synaptogenesis and Synaptic Plasticity
7:30 pm - 7:50 pm
"Perineuronal Nets and Parvalbumin Network Plasticity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Perineuronal Nets in a Mouse Model of Rett Syndrome: Regulation by Activity and Disease in the Hippocampus"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Interleukin-1β Alters Cortical Connectivity Through Dynamic Changes in IL-1β Receptor Localization and MHCI Signaling"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Activity-Dependent Regulation of Neuroligin-3 Levels at Excitatory and Inhibitory Synapses by the Sorting Receptor SorCS1"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"The Many Faces of LTP: Pathway Specific Variants of Memory-Related Plasticity"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Presynaptic Release, Postsynaptic Response, Calcium and Structural Plasticity
9:00 am - 9:20 am
"Molecular Mechanisms Regulating Presynaptic Calcium Channel Subtype Levels and Organization to Drive Neuronal Circuit Function"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Regulation of Glutamatergic Synapses by Wnt Signaling"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Role of Liquid-Liquid Phase Transitions in Shaping the Postsynaptic Density Scaffold: Why We Should Care"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Posttranscriptional Regulation of Calcium Dynamics in Autism Spectrum Disorders"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Template-Free Detection and Classification of Heterogeneous Membrane-Bound Complexes in Cryo-Electron Tomograms: Ionotropic Glutamated Receptors Analyzed In Situ "
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Defining the Organelles and Mechanisms of Unconventional Secretory Trafficking in Neuronal Dendrites"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Synaptic Circuit Structure and Function
7:30 pm - 7:50 pm
"Charting the Molecular Landscape of Diverse Synapses In Vivo "
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Super-Resolution Imaging of Inhibitory Synapses During Synaptic Plasticity"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Dendritic Channelopathies in Fragile X Syndrome"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Conservation of Ca2+ Regulation Among A-Type Potassium Channel Complexes"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Social Transmission and Buffering of Synaptic Plasticity"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Specificity in Regulating Synaptic Transmission
9:00 am - 9:20 am
"Synapse Specific Regulation of Neurotransmitter Release by Voltage-Gated K+ Channels"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Astrocyte Regulation of Neuronal Glutamate Receptors"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Synaptic and Memory Effects of Acute Traumatic Stresses: Molecules and Mechanisms"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"The Ultrastructure of Neuromodulatory Axons"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Circuit-Specific and Neuronal Subcellular-Wide Excitatory and Inhibitory Synaptic Balance in Cortical Pyramidal Cells"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"CaMKII: Form and Function of a Central Synaptic Regulator"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Keynote Session: Biochemical Computation in Single Dendritic Spines
5:30 pm - 5:45 pm
Introduction by Discussion Leader
5:45 pm - 6:45 pm
"Biochemical Computation in Single Dendritic Spines"
6:45 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
General Discussion
7:20 pm - 7:30 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure