Saturday 
 
 
1:00 pm - 5:00 pm 
	
Arrival and Check-in
 
 
						 
						 
					
						
						
3:00 pm - 3:15 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
 
 
						 
						 
					
						
						
3:15 pm - 4:00 pm 
	
Structural Studies of Cryo-EM Telomerases 
 
 
 
						 
						 
					
						
						
3:15 pm - 3:20 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
3:20 pm - 3:50 pm 
	
"Visualisation of Human Telomerase Holoenzyme by Cryo-EM" 
 
 
 
						 
						 
					
						
						
3:50 pm - 4:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
4:00 pm - 5:30 pm 
	
Poster Session 
 
 
						 
						 
					
						
						
5:30 pm - 7:30 pm 
	
Novel Sample and Grid Preparation Methods in Cryo-EM 
Novel sample and grid preparation methods for cryo-EM 
 
 
 
						 
						 
					
						
						
5:30 pm - 5:40 pm 
	
"Using Streptavidin Affinity Grids to Visualize Difficult Biological Samples" 
 
 
 
						 
						 
					
						
						
5:40 pm - 5:45 pm 
	
Discussion
 
 
						 
						 
					
						
						
5:45 pm - 5:55 pm 
	
"Use of the chamaleon for Cryo-EM Studies of Ribonucleotide Reductase" 
 
 
 
						 
						 
					
						
						
5:55 pm - 6:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
6:00 pm - 6:10 pm 
	
"Capturing Inhibited Assemblies of the Membrane Attack Complex" 
 
 
 
						 
						 
					
						
						
6:10 pm - 6:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
6:15 pm - 6:25 pm 
	
"Don't Purify in Vein! Structural Insights from Red Blood Cell Lysate" 
 
 
 
						 
						 
					
						
						
6:25 pm - 6:30 pm 
	
Discussion
 
 
						 
						 
					
						
						
6:30 pm - 6:40 pm 
	
"FIB-Milling for Single Particle Tomography" 
 
 
 
						 
						 
					
						
						
6:40 pm - 6:45 pm 
	
Discussion
 
 
						 
						 
					
						
						
6:45 pm - 6:55 pm 
	
"Parallel Cryo-ET on in situ Lamellae" 
 
 
 
						 
						 
					
						
						
6:55 pm - 7:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
7:00 pm - 7:10 pm 
	
"A Clonable Selenium Nanoparticle (cSeNP)" 
 
 
 
						 
						 
					
						
						
7:10 pm - 7:15 pm 
	
Discussion
 
 
						 
						 
					
						
						
7:15 pm - 7:30 pm 
	
General Discussion
 
 
						 
						 
					
						
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						 
						 
					
						
						
	Sunday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						 
						 
					
						
						
9:00 am - 11:00 am 
	
Emerging Tools for Studying Conformational Variability by Cryo-EM 
Emerging tools for studying conformational landscapes by cryo-EM and their biological applications 
 
 
 
						 
						 
					
						
						
9:00 am - 9:10 am 
	
"Dissecting the Dynamic Conformational Landscape of Functional RNAs by Cryo-EM" 
 
 
 
						 
						 
					
						
						
9:10 am - 9:15 am 
	
Discussion
 
 
						 
						 
					
						
						
9:15 am - 9:25 am 
	
"Conformation and Dynamics of the AAA ATPase p97" 
 
 
 
						 
						 
					
						
						
9:25 am - 9:30 am 
	
Discussion
 
 
						 
						 
					
						
						
9:30 am - 9:40 am 
	
"Using Volta Phase Plate to Study Heterogenous Human Translation Initiation Complexes" 
 
 
 
						 
						 
					
						
						
9:40 am - 9:45 am 
	
Discussion
 
 
						 
						 
					
						
						
9:45 am - 9:55 am 
	
"Particles of Confederation - Reliably Expanding Particle Sets by Machine-Learning Consensus" 
 
 
 
						 
						 
					
						
						
9:55 am - 10:00 am 
	
Discussion
 
 
						 
						 
					
						
						
10:00 am - 10:10 am 
	
"Zernikes3D: A Continuous Heterogeneity Tool for Cryo-EM Maps and Atomic Models" 
 
 
 
						 
						 
					
						
						
10:10 am - 10:15 am 
	
Discussion
 
 
						 
						 
					
						
						
10:15 am - 10:25 am 
	
"TomoFlow: A New Method for Analyzing Heterogeneous Subtomogram Datasets" 
 
 
 
						 
						 
					
						
						
10:25 am - 10:30 am 
	
Discussion
 
 
						 
						 
					
						
						
10:30 am - 10:40 am 
	
"In-situ Analysis of SARS-CoV-2 Spike Proteins on Intact Virions" 
 
 
 
						 
						 
					
						
						
10:40 am - 10:45 am 
	
Discussion
 
 
						 
						 
					
						
						
10:45 am - 10:55 am 
	
"Retrieving Biological Function from Time-Resolved Single-Particle Cryo-EM" 
 
 
 
						 
						 
					
						
						
10:55 am - 11:00 am 
	
Discussion
 
 
						 
						 
					
						
						
11:00 am - 12:30 pm 
	
Poster Session 
Coffee will be served in the poster area from 11:00 am - 11:30 am 
 
 
						 
						 
					
						
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						 
						 
					
						
						
1:30 pm - 2:30 pm 
	
Mentorship Component: Scientific Publishing 
 
 
 
						 
						 
					
						
						
1:30 pm - 1:35 pm 
	
Introduction by Discussion Leader
 
 
						 
						 
					
						
						
1:35 pm - 1:55 pm 
	
"Behind the Scenes: An Editor's Perspective on Publishing" 
 
 
 
						 
						 
					
						
						
1:55 pm - 2:00 pm 
	
Discussion
 
 
						 
						 
					
						
						
2:00 pm - 2:30 pm 
	
Panel Discussion 
Scientific Publishing 
 
 
 
						 
						 
					
						
						
2:30 pm - 3:00 pm 
	
Evaluation Period 
Fill in GRS Evaluation Forms 
 
 
						 
						 
					
						
						
3:00 pm 
	
Seminar Concludes