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Biology of Aging

Gordon Research Conference

Biology of Aging Across Scales: Molecular, Cellular, Organismal

August 3 - 8, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chairs

and

Vice Chairs

and

Renaissance Tuscany Il Ciocco

Via Giovanni Pascoli

Lucca (Barga), Lucca, Italy

Venue and Travel Information

Application Information

Applications for this meeting must be submitted by July 6, 2025. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the conference chair if more seats become available due to cancellations.

Conference Description

The Biology of Aging GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Biology of Aging" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Molecular Mechanisms of Aging and Longevity Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:10 pm	"Epigenetics of Aging"
8:10 pm - 8:15 pm	Discussion
8:15 pm - 8:35 pm	"Successful Neuronal Aging and Proteostasis: It Takes a Village"
8:35 pm - 8:40 pm	Discussion
8:40 pm - 9:00 pm	"Age-Related Changes in Gene Expression and Signaling in Mice and Rats: Including Changes in Activin Signaling and Mitochondria Signaling"
9:00 pm - 9:05 pm	Discussion
9:05 pm - 9:15 pm	Short Talk Selected from Poster Abstracts
9:15 pm - 9:20 pm	Discussion
9:20 pm - 9:30 pm	General Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Understudied Species and New Models for Aging Research Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:25 am	"Dogs as a Translational Model for the Biology of Aging"
9:25 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Equine Clinical Models of Naturally Occurring Miscarriage: A Unique Lens into Reproductive Aging"
9:50 am - 9:55 am	Discussion
9:55 am - 10:05 am	Short Talk Selected from Poster Abstracts
10:05 am - 10:10 am	Discussion
10:10 am - 10:20 am	Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am	Discussion
10:25 am - 10:55 am	Coffee Break
10:55 am - 11:15 am	"Aging and Whole-Body Rejuvenation in Extremely Long-Lived Planarians"
11:15 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Gerotherapeutic Intervention with Rapamycin to Target Aging and Health in Non-Human Primates"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Comparative Biology of Aging Discussion Leader:
6:00 pm - 6:05 pm	Introduction by Discussion Leader
6:05 pm - 6:25 pm	"Impact of Population Dynamics on the Genetics of Aging"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Bat Longevity and Epigenome Stability"
6:50 pm - 6:55 pm	Discussion
6:55 pm - 7:15 pm	"Multi-Omic Biomarkers of Longevity Across Species"
7:15 pm - 7:20 pm	Discussion
7:20 pm - 7:30 pm	Short Talk Selected from Poster Abstracts
7:30 pm - 7:35 pm	Discussion
7:35 pm - 7:45 pm	Short Talk Selected from Poster Abstracts
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Reproductive Aging Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:25 am	"Mechanisms of Ovarian Aging: A Target for Geroprotection in Women"
9:25 am - 9:30 am	Discussion
9:30 am - 9:50 am	"Evading Ageing: Metabolic and Proteostatic Adaptations in Oocytes"
9:50 am - 9:55 am	Discussion
9:55 am - 10:15 am	"Ovarian Aging"
10:15 am - 10:20 am	Discussion
10:20 am - 10:30 am	Short Talk Selected from Poster Abstracts
10:30 am - 10:35 am	Discussion
10:35 am - 11:05 am	Coffee Break
11:05 am - 11:25 am	"Naked Mole-Rat as a Model of Reproductive Aging"
11:25 am - 11:30 am	Discussion
11:30 am - 11:50 am	"Reproductive Aging and Longevity"
11:50 am - 11:55 am	Discussion
11:55 am - 12:05 pm	Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:30 pm	Poster Previews
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Inflammation, Transposable Elements and Aging Discussion Leader:
6:00 pm - 6:05 pm	Introduction by Discussion Leader
6:05 pm - 6:25 pm	"Programming and Reprogramming of Aging"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Exploring the Dark Genome: Somatic Retrotransposition in Cellular Senescence, Aging and Disease"
6:50 pm - 6:55 pm	Discussion
6:55 pm - 7:15 pm	"cGAS and Inflammation"
7:15 pm - 7:20 pm	Discussion
7:20 pm - 7:30 pm	Short Talk Selected from Poster Abstracts
7:30 pm - 7:35 pm	Discussion
7:35 pm - 7:45 pm	Short Talk Selected from Poster Abstracts
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Epigenetics and Nuclear Architecture During Aging Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:25 am	"Single-Cell Analysis of Human Hippocampus Uncovers an Age-Associated Epigenetic State Switch"
9:25 am - 9:30 am	Discussion
9:30 am - 9:50 am	"From Biomarker Discovery to a Candidate Therapeutic for Alzheimer’s Disease"
9:50 am - 9:55 am	Discussion
9:55 am - 10:05 am	Short Talk Selected from Poster Abstracts
10:05 am - 10:10 am	Discussion
10:10 am - 10:20 am	Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am	Discussion
10:25 am - 10:55 am	Coffee Break
10:55 am - 11:15 am	"Epigenetics of Aging"
11:15 am - 11:20 am	Discussion
11:20 am - 11:40 am	"Measuring Aging with AI"
11:40 am - 11:45 am	Discussion
11:45 am - 11:55 am	Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm	Discussion
12:00 pm - 12:10 pm	Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	New Technologies and Omics Approaches in Aging Discussion Leader:
6:00 pm - 6:05 pm	Introduction by Discussion Leader
6:05 pm - 6:25 pm	"Genomic Signatures of Human Immune System Aging and Reduced Vaccine Responses"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Age-Associated Somatic DNA Copy Number Alterations at Single-Cell Resolution"
6:50 pm - 6:55 pm	Discussion
6:55 pm - 7:15 pm	"Metabolomics Signatures of AD Risk, Metabolic Health and Longevity"
7:15 pm - 7:20 pm	Discussion
7:20 pm - 7:40 pm	"Genomic Basis of Longevity"
7:40 pm - 7:45 pm	Discussion
7:45 pm - 7:55 pm	Short Talk Selected from Poster Abstracts
7:55 pm - 8:00 pm	Discussion
8:00 pm - 9:00 pm	Dinner
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Anti-Aging Interventions, Human Aging and Stem Cells Discussion Leader:
9:00 am - 9:10 am	Introduction by Discussion Leader
9:10 am - 9:30 am	"Anti-Aging Drugs and the Search for Shared Mechanisms"
9:30 am - 9:35 am	Discussion
9:35 am - 9:55 am	"Clonal Hematopoiesis in Human Aging and Disease"
9:55 am - 10:00 am	Discussion
10:00 am - 10:10 am	Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am	Discussion
10:15 am - 10:25 am	Short Talk Selected from Poster Abstracts
10:25 am - 10:35 am	Discussion
10:35 am - 11:05 am	Coffee Break
11:05 am - 11:25 am	"Transcriptional and Epigenetic Mechanisms of Brain Aging and Neurodegeneration"
11:25 am - 11:30 am	Discussion
11:30 am - 11:50 am	"Targeting Cellular Cross-Talks in Cardiac Aging"
11:50 am - 11:55 am	Discussion
11:55 am - 12:05 pm	Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm	Discussion
12:10 pm - 12:20 pm	Short Talk Selected from Poster Abstracts
12:20 pm - 12:25 pm	Discussion
12:25 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:30 pm	Free Time
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 8:00 pm	Inter Organ Communication During Aging Discussion Leader:
6:00 pm - 6:05 pm	Introduction by Discussion Leader
6:05 pm - 6:25 pm	"Neural States as Conserved Modulators of Aging"
6:25 pm - 6:30 pm	Discussion
6:30 pm - 6:50 pm	"Sexual Dimorphism in Immunity and Ageing"
6:50 pm - 6:55 pm	Discussion
6:55 pm - 7:15 pm	"Remodeling of the ER as a Mechanism of Aging"
7:15 pm - 7:20 pm	Discussion
7:20 pm - 7:30 pm	Short Talk Selected from Poster Abstracts
7:30 pm - 7:35 pm	Discussion
7:35 pm - 7:45 pm	Short Talk Selected from Poster Abstracts
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:00 pm	General Discussion
8:00 pm - 9:00 pm	Dinner
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute On Aging of the National Institutes of Health under Award Number R13AG094199. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

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Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,610.00

Conferee Shared Room:

$1,325.00

Conferee Off-Site:

$915.00

Guest Single Room:

$1,420.00

Guest Shared Room:

$1,135.00

Guest Off-Site:

$725.00

Child 4-12 yrs Shared Room:

$568.00

Child 4-12 yrs Off-Site:

$363.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$62.00

Bus Departing:

$62.00

Additional Fee Info

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