Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Keynote Session: Microbial Toxins and Pathogenicity |
| Discussion Leader: Andrew Camilli (Tufts University School of Medicine, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:35 pm | Pascale Cossart (Pasteur Institute, France) "Listeria monocytogenes: A Unique Model in Infection Biology" |
8:35 pm - 8:50 pm | Discussion |
8:50 pm - 9:05 pm | Aaron Whiteley (University of California, Berkeley, USA) "Why Is the PAMP Cyclic Di-AMP Essential in Listeria monocytogenes?" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:25 pm | Cara Mozola Forsberg (University of Washington, USA) "What P. aeruginosa Traits Promote Chronic Infection of CF Airways?" |
9:25 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Toxins - Action, Targeting and Structure |
| Discussion Leader: Joseph Barbieri (Medical College of Wisconsin, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Borden Lacy (Vanderbilt University School of Medicine, USA) "Structure and Function of Clostridium difficile Toxins, TcdA and TcdB" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Neal Alto (University of Texas Southwestern Medical Center, USA) "The Biochemistry of Immune Suppression by Bacterial Pathogens" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Group Photo / Coffee Break |
10:45 am - 11:10 am | Jorge Galan (Yale School of Medicine, USA) "Salmonella typhi's Typhoid Toxin" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Jimmy Ballard (University of Oklahoma Health Sciences Center, USA) "Exploring Variant Forms of Clostridium difficile TcdB" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | Seema Mattoo (Purdue University, USA) "From Bacterial Pathogens to ER Homeostasis: Fic Proteins in Cellular Signalling" |
12:15 pm - 12:20 pm | Discussion |
12:20 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Regulation of Virulence |
| Discussion Leader: Peggy Cotter (University of North Carolina at Chapel Hill, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Theresa Koehler (McGovern Medical School, University of Texas Health Science Center at Houston, USA) "What Does the Phophoenolpyruvate Phosphotransferase System Have to Do with Bacillus anthracis Virulence?" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Victoria Stone (University of California, Santa Cruz, USA) "Control of Yersinia Virulence Factor Expression and Pathogenesis by the Iron Sulfur Cluster Transcription Factor IscR" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Melanie Blokesch (École Polytechnique Fédérale de Lausanne, Switzerland) "The Yin and Yang of Type VI Secretion Regulation in Pandemic Vibrio cholerae" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Pathogenesis |
| Discussion Leader: Beth McCormick (University of Massachusetts Medical School, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Arturo Zychlinsky (Max Planck Institute for Infection Biology, Germany) "Antimicrobial Activity of Neutrophils" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Joan Mecsas (Tufts University School of Medicine, USA) "Interactions Between Yersinia and Innate Immune Cells" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Sarah Fortune (Harvard T.H. Chan School of Public Health, USA) "Identifying Determinants of the Outcome of M. tuberculosis Infection Through Single Cell Analyses" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Michael Bachman (University of Michigan, USA) "Insights into Klebsiella pneumoniae Pathogenesis from Patients and Their Animal Models" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Joanne Engel (University of California, San Francisco, USA) "Defining the Chlamydia Inclusion Membrane Protein-Host Protein Interactome" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Pathogen Evolution |
| Discussion Leader: William Goldman (University of North Carolina at Chapel Hill, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Nels Elde (University of Utah, USA) "Experimental Evolution of Pathogen Populations" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Kim Seed (University of California, Berkeley, USA) "Fighting with Phages: How Epidemic Vibrio cholerae Defends Against Viral Attack" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Wyndham Lathem (Feinberg School of Medicine, Northwestern University, USA) "From Mild to Murderous: How Yersinia pestis Evolved into an Efficient Killer" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Basics of Bacterial Pathogens |
| Discussion Leader: Heran Darwin (New York University School of Medicine, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Miriam Braunstein (University of North Carolina at Chapel Hill, USA) "Unraveling the Role of the SecA2 Pathway in Mycobacterium tuberculosis in Macrophages" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Michael Federle (University of Illinois at Chicago, USA) "Social Appearances: Quorum Sensing Control of the Cell Envelope of Streptococcus pyogenes" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Nina Salama (Fred Hutchinson Cancer Research Center, USA) "Bacterial Adaptations for Life in the Stomach" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Andrew Darwin (New York University School of Medicine, USA) "Pushing the Envelope in Bacterial Pathogenesis" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Vincent Lee (University of Maryland, College Park, USA) "Discovery of Signaling Nucleotide Receptors and Their Inhibitors" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Close Encounters with the Host Cell |
| Discussion Leader: Mary O'Riordan (University of Michigan Medical School, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Barbara Kazmierczak (Yale University, USA) "Phenotypic Heterogeneity in Pseudomonas Pathogenesis" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Raphael Valdivia (Duke University Medical Center, USA) "Mechanisms of Cell Survival in Chlamydia Infected Cells" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Alison Criss (University of Virginia, USA) "Flirting with Disaster: How Neisseria gonorrhoeae Survives Encounters with Neutrophils" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Innate Immune Responses and Pathogenesis |
| Discussion Leader: Manuela Raffatellu (University of California, Irvine, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jyothi Rengarajan (Emory University, USA) "Mycobacterium tuberculosis Modulation of Innate-Adaptive Crosstalk" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | David Underhill (Cedars-Sinai Medical Center, USA) "Innate Immune Recognition of Bacterial Cell Walls" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:45 am | Coffee Break |
10:45 am - 11:10 am | Jorge Henao-Mejia (University of Pennsylvania, USA) "Regulation of Immune Host Defense by Novel Long Non-Coding RNAs" |
11:10 am - 11:20 am | Discussion |
11:20 am - 11:45 am | Ken Cadwell (New York University School of Medicine, USA) "Autophagy and Enteric Bacterial Infections" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:20 pm | Sunny Shin (University of Pennsylvania, USA) "Overcoming Bacterial-Encoded Virulence Activities to Initiate Innate Immune Defense" |
12:20 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Keynote Session: Perspectives on the Future of Host-Pathogen Interaction Research |
| Discussion Leader: Karen Ottemann (University of California, Santa Cruz, USA) |
5:30 pm - 5:40 pm | Introduction by Discussion Leader |
5:40 pm - 6:25 pm | Eric Skaar (Vanderbilt University, USA) "The Intersection of Nutrition and Infection at the Host-Pathogen Interface" |
6:25 pm - 6:40 pm | Discussion |
6:40 pm - 6:55 pm | Lillian Juttukonda (Vanderbilt University, USA) "Dietary Manganese and the Host Protein Calprotectin Promote Staphylococcal Infection of the Hear" |
6:55 pm - 7:00 pm | Discussion |
7:00 pm - 7:15 pm | Damien Keogh (SCELSE, Nanyang Technological University, Singapore) "Enterococcus faecalis Powers Biofilm Formation Through Extracellular Electron Transfer of Iron" |
7:15 pm - 7:20 pm | Discussion |
7:20 pm - 7:30 pm | General Discussion |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |