Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Host-Pathogen-Microbiota Interactions
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 7:55 pm
"Getting Your Neutrophil: Hepoxilin A3 (HXA3)-Dependent Neutrophil Migration During Streptococcus pneumoniae Infection"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"A Multi-Surface Recognition Strategy Constrains Bacterial Immune Evasion"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"Campylobacter jejuni , Fecal Metabolites and a Novel Iron Uptake System"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:20 pm
"Salmonella , the Host and Its Gut Microbiota"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Dynamics of Pathogens
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"Chemical Biology of Mycobacterium tuberculosis Pathogenesis"
9:30 am - 9:35 am
Discussion
9:35 am - 10:00 am
"The Bacterial Accessory Genome: Concealed Carry"
10:00 am - 10:05 am
Discussion
10:05 am - 10:30 am
Group Photo / Coffee Break
10:30 am - 10:55 am
"Dissemination of Listeria monocytogenes Within Its Host"
10:55 am - 11:00 am
Discussion
11:00 am - 11:25 am
"Modifications to Lipid A Are Dynamic in Response to Host Environmental Conditions"
11:25 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Friend or Foe: Membrane Vesicles of Bacterial Pathogens"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:25 pm
"A Conserved Flavin-Mediated Mechanism of Extracellular Electron Transfer"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Aspects of the Microbiota and Pathogen Virulence in Disease
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:00 pm
"Dissection of the Roles of Multifunctional Borrelia burgdorferi Adhesins In Vivo "
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Sensing Spatial Location in the Intestine"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 9:10 pm
"Adaptation of the Microbiota in Cystic Fibrosis"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Toxins and Effector Proteins Pave the Way
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"How Pathogens Coerce Pyrin to Drop Its Guard in Lymphoid and Mucosal Tissues"
9:30 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Staphylococcus aureus Toxin: Patterning the Host-Bacterial Interaction"
10:00 am - 10:05 am
Discussion
10:05 am - 10:30 am
"Staphylococcus aureus Follows a 'DARC' Path to Lethal Infections"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Effect the Unexpected: Metaeffectors in Legionella and Beyond"
11:30 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Structural Analysis of the Legionella Dot/Icm T4SS"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Pasteurella multocida Toxin Hijacks the Host Cell Metabolism"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Toxins: Action, Targeting and Structure
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 8:00 pm
"Entry Pathways of the Clostridial Neurotoxins"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"The How and Why of Bordetella Adenylate Cyclase Toxin"
8:30 pm - 8:35 pm
Discussion
8:35 pm - 9:00 pm
"Unexpected Convergence Between Bacterial Development and Intracellular Egress"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Mechanisms of Enterococcus faecalis Persistence During Chronic Wound Infections"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Pathogenesis and New Approaches
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"Helicobacter pylori Diversity and Gastric Cancer Risk"
9:30 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Single Cell Behavior During Infection and Antibiotic Resistance"
10:00 am - 10:05 am
Discussion
10:05 am - 10:30 am
"Systems Genetic Analysis of Tuberculosis Susceptibility"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Mechanisms of Gene Diversification in the Pathogenic Neisseria "
11:30 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"The Impact of Biogeography on Pathogenesis During Polymicrobial Infection"
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Persistence, Metabolic Flexibility and Antibiotic Resistance in Staphylococcus aureus "
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Close Encounters with the Host Cell
7:30 pm - 7:55 pm
"Integration of Signal Transduction Pathways for Survival of Bordetella in both Mammalian and Non-Mammalian Eukaryotic Hosts"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:25 pm
"Modulation of Blood Brain Barrier Permeability During Group B Streptococcal Meningitis"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:55 pm
"You're Hot and You're Cold: Neurotransmitters Modulation of Bacterial Virulence Gene Expression"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:25 pm
"S-Nitrosylation of a Virulence Regulator Shapes Vibrio cholerae Intestinal Infection Landscapes"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immune Responses and Pathogenesis
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:30 am
"Neutrophil Plasticity and Helicobacter pylori Pathogenesis"
9:30 am - 9:35 am
Discussion
9:35 am - 10:00 am
"A Unified Mechanism for Innate Detection of Diverse Bacterial Toxins"
10:00 am - 10:05 am
Discussion
10:05 am - 10:30 am
"Regulation of Inflammatory Cell Death During Bacterial Infection"
10:30 am - 10:35 am
Discussion
10:35 am - 11:05 am
Coffee Break
11:05 am - 11:30 am
"Cells on Fire: Control of Inflammation and Host Defense by Cellular Stress Responses"
11:30 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Outcomes of the Interactions Between Neutrophils and Mycobacterium tuberculosis "
12:00 pm - 12:05 pm
Discussion
12:05 pm - 12:25 pm
"Control of Innate Immune Cell Activation by Staphylococcus aureus "
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 5:30 pm
Poster Session
5:30 pm - 7:30 pm
Keynote Session: Host-Pathogen Biochemistry
5:30 pm - 5:40 pm
"Bacterial cGAS-Like Enzymes at the Host-Pathogen Interface"
5:40 pm - 5:45 pm
Discussion
5:45 pm - 5:55 pm
"The Mitochondrial Protein CARD19 Regulates a Cell Death Checkpoint Downstream of Caspase Activation and Gasdermin D Cleavage"
5:55 pm - 6:00 pm
Discussion
6:00 pm - 6:35 pm
"Molecular Mechanisms of Host Cell Manipulation by Legionella "
6:35 pm - 6:45 pm
Discussion
6:45 pm - 7:20 pm
"Black Spot, Black Death, Black Pearl: The Tales of Bacterial Effectors"
7:20 pm - 7:30 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure