1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: New Insights into Insulin Secretion
Lauren Clark (University of Wisconsin - Madison, United States)
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
Alan Attie (University of Wisconsin-Madison, United States) "Genetic Dissection of Insulin Secretion"
4:20 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Cellular Principles Underlying Disease and Physiology
Sukrati Kanojia (Indiana University, United States)
7:30 pm - 7:45 pm
Najla Arshad (Yale University School of Medicine, United States) "Dysregulation of Major Histocompatibility Complex Class I (MHC-I) Trafficking and Function by SARS-CoV-2 Accessory Proteins"
7:45 pm - 7:50 pm
7:50 pm - 8:05 pm
Jaidev Bapat (University of Colorado Anschutz Medical Campus, United States) "CASC4 Drives Anoikis Resistance in High Grade Serous Ovarian Cancer Through Recycling of EGFR"
8:05 pm - 8:10 pm
8:10 pm - 8:25 pm
Jinhee Hwang (Beckman Research Institute of City of Hope, United States) "Doc2b Enrichment Averts Dysfunctional GLUT4 Translocation in a STX4 Dependent Pathway in Muscle Cells"
8:25 pm - 8:30 pm
8:30 pm - 8:45 pm
Farhana Taher Sumya (UAMS, United States) "Development and Characterization of a Novel Cellular Model for COG4 CDG-II Diseases"
8:45 pm - 8:50 pm
8:50 pm - 9:05 pm
Sisi Lai (Case western reserve university, United States) "Identify Proinsulin Regulators with Mouse Genetics and CRISPR Screen"
9:05 pm - 9:10 pm
9:10 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Cellular and Signaling Mechanisms Underlying Protein Trafficking and Secretion
Rita Mueller (Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute, Germany)
9:00 am - 9:15 am
Rosaria Di Martino (Institute for Endocrinology and Experimental Oncology (IEOS-CNR) Napoli, Italy, Italy) "Autoregulatory Circuit Regulating Basolateral Cargo Export From the TGN: Role of the Orphan Receptor GPRC5A in PKD Signaling and Cell Polarity"
9:15 am - 9:20 am
9:20 am - 9:35 am
Alexander Stockhammer (Freie Universität Berlin, Germany) "Trans-Golgi Network (TGN)-Derived ARF1-Positive Tubules Serve as an Intermediate Sorting Station Between the Golgi Apparatus and the Endo-Lysosomal System"
9:35 am - 9:40 am
9:40 am - 9:55 am
Mengxiao Ma (Stanford University, United States) "Regulan (RGLN) Links N-Glycosylation in the Endoplasmic Reticulum to Cellular Sensitivity to Extracellular Signals"
9:55 am - 10:00 am
10:00 am - 10:15 am
Jie Li (New York University School of Medicine, United States) "SKP1 Phosphorylation Regulates the Switch Between Autophagy and Unconventional Secretion"
10:15 am - 10:20 am
10:20 am - 10:35 am
Taryn Olivas (Yale University, United States) "ATG9 Vesicles are Incorporated into Nascent Autophagosome Membranes"
10:35 am - 10:40 am
10:40 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Novel Techniques in Membrane Trafficking
Maohan Su (Yale School of Medicine, United States)
1:30 pm - 2:15 pm
Thomas Wollert (Institut Pasteur Paris, France) "Cellular Recycling in Health and Disease – Molecular Mechanisms of Autophagy"
2:15 pm - 2:30 pm
2:30 pm - 3:00 pm
Complete the GRS Evaluation Forms; Election of Future Chair(s)